δ-Valerolactone DVL Delta-Valerolactone CAS 542-28-9

Tree Chem δ-Valerolactone (DVL), also known as 5-Valerolactone or 2-Oxepanone, is a colorless transparent liquid produced under controlled temperature and catalytic conditions to achieve high purity and low acidity. It serves as an essential monomer and solvent, compatible with a wide range of organic compounds.

We manufacture and supply DVL in multiple grades for polymerization feedstock, coating formulations, cleaning agents, and fine chemical synthesis, ensuring reliable batch-to-batch consistency. For more information, please contact info@cntreechem.com.

Specification

Basic Information

Technical Specification

Applications

Pharmaceutical Industry

• Delta-Valerolactone (DVL) serves as a versatile intermediate and solvent in pharmaceutical synthesis. Its cyclic ester structure allows it to participate in various ring-opening reactions to produce valuable intermediates for active pharmaceutical ingredients (APIs). It is particularly used in the synthesis of pyrrolidone and caprolactone derivatives that function as solvents, stabilizers, and excipients in drug formulations. Due to its mild reactivity and low toxicity, DVL is employed as a solvent in reactions requiring precise control, such as esterification, amidation, and transesterification processes.
• In controlled-release drug delivery systems, DVL-based polyesters are applied to form biodegradable carriers. These materials ensure gradual drug release and biocompatibility, making them suitable for long-acting injectable and implantable drug systems. Furthermore, DVL-derived monomers are explored in the development of lactone-based polymers used in medical coatings and encapsulation materials.

Polymer and Coatings Industry

• In the polymer field, Delta-Valerolactone is a key monomer and co-monomer in the preparation of biodegradable and high-performance polymers. It undergoes ring-opening polymerization (ROP) to produce poly(δ-valerolactone), which is utilized in biodegradable plastics, packaging, and agricultural films. When copolymerized with ε-caprolactone or glycolide, it provides adjustable mechanical strength and degradation rate, making it valuable for eco-friendly materials and biomedical applications.
• In coatings and adhesive systems, DVL functions as a reactive diluent and coalescent agent, improving film formation, flexibility, and adhesion. It enhances compatibility with resins such as acrylics, epoxies, and polyesters, resulting in superior coating durability and resistance to cracking. DVL-modified polyurethane coatings also show excellent weather and chemical resistance, suitable for automotive and industrial uses.

Agrochemical Industry

• In the agrochemical industry, DVL is applied as an intermediate for synthesizing herbicides, fungicides, and plant growth regulators. It serves as a building block in the preparation of lactone-containing agrochemical compounds, enhancing bioactivity and environmental degradability. DVL’s favorable solvency profile makes it a suitable solvent and co-solvent for emulsifiable concentrates (ECs) and suspension concentrates (SCs).
• Additionally, DVL-based polymers are used in controlled-release formulations for agrochemicals. These polymers slowly degrade under environmental conditions, releasing active ingredients over time, improving efficiency, and reducing environmental impact. Such applications are increasingly valued in sustainable agricultural practices.

Electronics and Industrial Cleaning

• Delta-Valerolactone functions as a high-boiling, low-volatility solvent in cleaning agents for electronic components and precision instruments. Its ability to dissolve organic residues, flux, and polymeric contaminants without damaging metal surfaces makes it ideal for printed circuit board (PCB) and semiconductor cleaning solutions. When blended with other polar solvents such as NMP or GBL, DVL improves the removal efficiency of post-etch residues and photoresists in wafer manufacturing.
• In industrial degreasing and polymer film cleaning, DVL’s balanced polarity ensures safe and effective removal of organic contaminants. Its relatively low toxicity and biodegradability also support its use as a green solvent in surface cleaning and maintenance formulations.

Personal Care and Fragrance Applications

• DVL exhibits a light, sweet odor and acts as a precursor for fragrance and flavor compounds such as δ-decalactone and γ-nonalactone, which provide creamy and fruity notes. It is also utilized as a solvent and fixative in fragrance formulations, enhancing the longevity and diffusion of scent components.
• In cosmetics and personal care formulations, DVL can function as an emollient and carrier solvent in creams, lotions, and serums, offering smooth texture and skin compatibility. Additionally, DVL-derived polyesters are explored in the development of biodegradable microcapsules for encapsulating fragrances or active ingredients.

Other Industrial Applications

• DVL serves as a feedstock for polymeric plasticizers, resins, and lubricants. In lubricant formulations, it acts as a viscosity modifier and film-forming agent, enhancing thermal stability and lubricity. DVL-based esters are increasingly used in synthetic lubricants for machinery and automotive applications due to their biodegradability and low volatility.
• In specialty chemicals, Delta-Valerolactone contributes to producing polyester polyols and surfactant intermediates. Its ring-opening capability allows the formation of hydroxyl-functionalized products used in polyurethane foam and elastomer manufacturing. DVL’s combination of reactivity, stability, and low environmental impact continues to drive its adoption across diverse industrial fields.

Storage & Handling

• Store in a cool, dry, and well-ventilated place away from heat sources.
• Keep containers tightly closed to prevent oxidation or hydrolysis.
• Avoid exposure to strong acids, alkalis, and oxidizing agents.
• Recommended storage temperature: below 30 °C.
• Use stainless steel or coated containers for transportation and long-term storage.

Usage Notice

• Handle under ventilated conditions; avoid inhaling vapor or mist.
• Use protective gloves, goggles, and lab coats when handling.
• Avoid prolonged skin or eye contact; rinse immediately with clean water if contact occurs.
• Prevent contamination with moisture or reactive substances.
• Follow local environmental and safety regulations when disposing of waste materials.
• Pharmaceutical intermediate synthesis: DVL 100 parts, reactant 50 parts, catalyst 1 part — used for ring-opening reaction to form lactone derivatives.
• Biodegradable polymer: DVL 100 parts, ε-caprolactone 50 parts, catalyst 0.5 part — produces flexible and eco-friendly polyesters.
• Coating formulation: resin 40–60%, DVL 10–20%, solvent 20–30%, additives 2–5% — enhances film formation and adhesion.
• Adhesive formulation: polymer 30–50%, DVL 10–25%, co-solvent 15–25%, curing agent 2–5% — improves elasticity and bond strength.
• Pesticide EC: active 10–60%, solvent 30–60%, DVL 0.5–10%, emulsifier 5–15% — enhances solubility and stability.
• Electronics cleaning agent: DVL 20–50%, co-solvent 30–50%, surfactant 1–5%, water balance — removes residues and flux effectively.
• Fragrance blend: aroma compound 80–90%, DVL 5–10%, fixative 1–3% — improves scent diffusion and retention.
• Lubricant formulation: base oil 80–90%, DVL-derived ester 5–15%, additive 1–5% — enhances viscosity and wear resistance.

Packaging

• 200 kg steel drum
• Optional customized packaging available