Dodecylamine A12 1-Aminododecane CAS 124-22-1

Tree Chem manufactures Dodecylamine CAS 124-22-1 for customers seeking to purchase high-quality C12 primary amines used in surfactants, ore flotation collectors, textile processing agents, and industrial chemical intermediates. Its excellent reactivity and balanced carbon-chain distribution make it suitable for downstream quaternary ammonium salt synthesis, ethoxylated amines, and alkylamide production.

With a clean liquid appearance and controlled impurity levels, Dodecylamine provides stable performance in corrosion inhibitors, lubricant additives, emulsifiers, antistatic agents, and various specialty chemicals. It delivers strong hydrophobicity and surface activity, making it suitable for a wide range of industrial formulations. For technical consultation or bulk supply, please contact info@cntreechem.com.

Specification

Basic Information

Technical Specification

Applications

Surface Surfactant and Cleaning Industry

• Dodecylamine is a core raw material for cationic and nonionic surfactants, and the surfactant industry is the single largest downstream consumer. Through quaternization it is converted into dodecyl trimethyl ammonium chloride (DTAC), dodecyl dimethyl benzyl ammonium chloride (DDBAC) and related cationic species, which provide conditioning, antistatic and bactericidal functions in hair-care, fabric-care and disinfectant products. Its shorter C₁₂ chain gives higher mobility and stronger penetration than longer-chain analogues, so dodecylamine-based derivatives perform particularly well in fine cleaning and high-efficiency wetting scenarios.
• In daily chemical applications, high-purity dodecylamine is first converted into cosmetic-grade DTAC or similar quats before being formulated into hair conditioners. These quats adsorb onto hair keratin, reduce friction, improve wet combing and suppress static, while co-formulated fatty alcohols and humectants stabilize the emulsion and improve feel. In industrial cleaning, dodecylamine polyoxyethylene ethers (for example, EO=5) are used together with fatty alcohol ethoxylates and triethanolamine to build metal cleaners that combine rapid wetting and strong emulsification power with rust inhibition; at moderate temperatures and short contact times, such formulations can remove more than ninety-eight percent of oils from steel and aluminum parts while providing temporary corrosion protection.

Water Treatment Industry

• In water treatment, dodecylamine is valued as a corrosion inhibitor, bactericide precursor and charge-modifying coagulant component. As a free amine or protonated salt, it adsorbs on metal surfaces and forms compact monomolecular films that act as barriers to water and dissolved oxygen, reducing corrosion of carbon steel in circulating-cooling-water systems. Compared with traditional inorganic inhibitors used at much higher dosages, dodecylamine-based systems achieve high inhibition efficiency with only a few ppm of active ingredient, making them attractive from both cost and environmental perspectives.
• By quaternization with benzyl chloride, dodecylamine is converted to DDBAC, a powerful cationic biocide widely used in oilfield injection water and industrial water systems. In high-salinity, elevated-temperature environments, DDBAC blended with nonionic dodecylamine ethoxylates and auxiliary biocides such as isothiazolinones can quickly destroy cell membranes of sulfate-reducing bacteria and general bacteria, maintaining ultra-low microbial counts for two to three days after dosing. Dodecylamine hydrochloride and related salts can also be used to neutralize the negative charge of colloids in water, enhancing flocculation and sedimentation in systems where charge destabilization is required alongside corrosion control.

Textile Printing and Dyeing Industry

• In textile printing and dyeing, dodecylamine derivatives act mainly as softening agents, antistatic agents and acid-dye fixing agents. Quaternized products such as dodecyl trimethyl ammonium bromide (DTAB) are formulated into cotton fabric softeners that deposit on the fiber surface, reduce inter-fiber friction and impart a fluffy, soft hand. When combined with betaine-type surfactants and suitable emulsifiers, these systems offer excellent wash-resistant softness without yellowing or loss of whiteness, even after dozens of laundering cycles.
• For protein fibers such as silk and wool dyed with acid dyes, dodecylamine hydrochloride is used as a fixing agent. Its cationic nature allows it to form ionic pairs with anionic dye molecules and to interact with acidic groups on the fiber surface, thereby increasing wet-rub and wash fastness. Formulations containing dodecylamine hydrochloride with plasticizing polyols and controlled acidity can raise wet-rub fastness on silk by one to two grades while maintaining the natural luster and drape of the fabric. In antistatic finishing of synthetic fibers, suitable dodecylamine derivatives are chosen to reduce surface resistivity below 10⁹ ohms and to provide durable static control compatible with standard dyeing and finishing sequences.

Rubber and Plastics Industry

• The rubber and plastics industries use dodecylamine primarily as an antistatic agent, mold-release agent and vulcanization-auxiliary component. In polyolefin films, its ethoxylated derivatives are incorporated as internal antistatic agents, migrating gradually to the surface and forming conductive layers that dissipate charge. Compared with traditional glyceride-based antistats, dodecylamine ethoxylates offer longer-lasting antistatic performance and can maintain surface resistivity in the 10⁷–10⁸ ohm range for extended periods under varying humidity, all while preserving high transparency in packaging films.
• In rubber processing, dodecylamine is applied as an external mold-release component, particularly for nitrile rubber seals and similar parts. When sprayed or brushed onto mold surfaces in suitable aqueous emulsions containing silicones and nonionic emulsifiers, it forms thin lubricating films that sharply reduce demolding force. At the same time, it does not interfere with sulfur cure systems or degrade surface appearance, allowing high-gloss parts and unchanged cure times. As a vulcanization auxiliary, dodecylamine can participate in accelerator systems, improving cure efficiency and supporting uniform crosslink structures in selected rubber compounds.

Mineral Flotation and Asphalt Emulsifiers

• In mineral processing, dodecylamine is an efficient cationic collector for quartz, potash and related nonmetallic minerals. Its protonated amine group interacts with mineral surface silanol or other acidic sites, rendering the surface hydrophobic and enabling selective flotation separation under optimized pH and reagent conditions. In quartz-sand flotation for photovoltaic glass feedstock, dosages on the order of a few tenths of a kilogram per ton of ore are sufficient to capture gangue phases and produce high-purity silica concentrates suitable for glass production. The shorter C₁₂ chain compared with octadecylamine can offer faster kinetics and better control of froth behavior in fine-particle systems.
• In the asphalt sector, dodecylamine is converted into dodecylamine hydrochloride and used as the active cationic component in asphalt emulsifiers. When formulated with nonionic co-emulsifiers, these salts lower the interfacial tension between asphalt and water and provide positive charges on droplet surfaces, stabilizing emulsions for road-construction applications. Such emulsifiers allow the production of cationic asphalt emulsions that remain storage-stable for at least several dozen hours without phase separation and that can be applied at much lower temperatures than hot-mix asphalt, reducing energy consumption and enabling thin-layer treatments such as micro-surfacing and slurry seals.

Biomedicine and Emerging High-End Uses

• In biomedicine, high-purity dodecylamine is used as a functional building block for liposomal carriers and other advanced delivery systems. Its hydrophobic C₁₂ chain can insert into lipid bilayers, while the amine group can be functionalized or protonated to modulate surface charge and to attach targeting ligands. In anticancer drug-delivery systems, dodecylamine-modified liposomes have been used to enhance drug accumulation in tumor tissues, increasing local drug concentration several-fold compared with non-modified carriers and reducing off-target toxicity to normal cells.
• Beyond drug delivery, dodecylamine also appears in research on novel materials for energy and environmental applications, where its amphiphilic character supports the preparation of specialty surfactants, functionalized nanoparticles and interface-modifying agents. Its high reactivity enables the design of tailored derivatives for uses in high-purity processes, including specialty electronics chemicals and high-end water-treatment products, and industry trends indicate increasing demand for high-purity grades as downstream applications move toward higher performance and stricter regulatory standards.

Market-Driven Specifications and Development Directions

• Across all these industries, the required technical specification of dodecylamine depends on the sector and final application. Surface-active and personal-care uses typically demand high-purity material with low color, controlled iodine value, narrow amine-value ranges and minimal heavy metals and residues to ensure mildness and stability. Water-treatment and mineral-flotation applications can tolerate industrial grades with slightly lower purity, provided that amine value and water content meet process requirements and that the product maintains good thermal stability under operating conditions.
• The report also highlights a clear market shift toward high-purity and functionalized derivatives, including narrow-distribution ethoxylates and optimized quaternary salts. At the same time, regulatory and sustainability pressures are driving interest in bio-based dodecylamine and environmentally friendlier formulations, as well as in integrated production chains that move from basic amine supply to high-value, customized functional additives for specific downstream industries.

Storage & Handling

• Keep containers tightly closed and stored in a cool, dry area.
• Avoid sunlight and high temperature.
• Prevent contact with acids and oxidizing substances.
• Maintain clean and dry equipment during handling.
• Ground all transfer equipment to prevent static discharge.

Usage Notice

• Warm gently if crystallization occurs at low temperature.
• Avoid moisture contamination.
• Wear protective gloves and eyewear.
• Ensure compatibility when mixed with reactive compounds.
• Follow local safety standards for storage and transport.
• Hair-conditioner formulation uses 1.5–2.5% dodecyl trimethyl ammonium chloride made from high-purity dodecylamine, with 2.0–3.0% stearyl alcohol, 3.0–5.0% glycerin, 0.5–1.0% panthenol and a small amount of citric acid in water to improve wet combing, reduce static and match scalp pH.
• Industrial metal-cleaner formulation contains 4.0–6.0% dodecylamine polyoxyethylene ether with EO=5, 3.0–5.0% AEO-9, 2.0–3.0% triethanolamine, 1.0–2.0% borax, 2.0–4.0% isopropanol and the balance deionized water, used after dilution at about 1:20 to remove more than ninety-eight percent of oils at fifty degrees Celsius.
• Circulating-cooling-water corrosion-inhibitor formulation doses 5–8 ppm dodecylamine together with 10–15 ppm sodium molybdate, 2–4 ppm zinc salt, 8–12 ppm polymaleic anhydride and pH adjustment with sodium hydroxide to reduce carbon-steel corrosion rates to 0.02 mm per year or less.
• Oilfield injection-water biocide formulation contains 30–40% DDBAC derived from dodecylamine, 5–8% dodecylamine polyoxyethylene ether with EO=3, 5–10% ethylene glycol butyl ether, 2–3% isothiazolinone and the balance water, dosed at 100–200 ppm to reduce sulfate-reducing bacteria to ten cells per milliliter or below.
• Cotton-fabric softener formulation uses 8–12% dodecyl trimethyl ammonium bromide made from dodecylamine, 3–5% fatty-amide propyl betaine, 2–4% glycerol monostearate and 0.1–0.2% citric acid in water, applied by padding with a pick-up of 70–80% to obtain durable softness without yellowing.
• Acid-dye fixing-agent formulation for silk uses 15–20% dodecylamine hydrochloride, 5–8% PEG-400, 1–2% acetic acid, 5–10% ethanol and the balance water at a working concentration of 10–15 g/L and about sixty degrees Celsius to raise wet-rub fastness to grade four or higher.
• Polypropylene film internal-antistatic formulation uses 97.0–98.0% homopolymer PP resin, 1.5–2.0% dodecylamine polyoxyethylene ether with EO=6, 0.3–0.5% calcium stearate, 0.1–0.2% antioxidant 1010 and 0.1–0.2% sorbitol-type nucleating agent to maintain surface resistivity in the 10⁷–10⁸ ohm range while preserving at least ninety percent light transmittance.
• Rubber demolding-agent formulation for nitrile rubber seals contains 5–8% dodecylamine, 3–5% silicone oil of about 100 cSt, 2–4% AEO-7, 3–5% propylene glycol and the balance deionized water, diluted ten- to twenty-fold for spraying to cut demolding force from roughly 120 newtons to about 45 newtons.
• Quartz-sand flotation collector formulation doses 0.1–0.3 kilograms of dodecylamine per ton of ore under appropriate pH conditions to render quartz hydrophobic and raise product SiO₂ content to above 99.5 percent.
• Cationic asphalt-emulsion formulation uses 3–5% dodecylamine hydrochloride together with Span-80 as the emulsifier system to produce emulsions with storage stability of at least seventy-two hours and application temperatures around fifty degrees Celsius.
• High-purity dodecylamine-based liposomal carrier formulation incorporates dodecylamine-modified lipids into liposome shells so that antitumor drugs achieve three- to five-fold higher accumulation in tumor tissue compared with non-modified carriers while reducing toxicity to normal cells.

Packaging

• 160 kg iron drum
• Export-grade sealed packaging