EDTMPS Sodium Salt CAS 22036-77-7

Tree Chem produces EDTMPS CAS 22036-77-7 for customers requiring a dependable phosphonate chelating agent with excellent scale inhibition and corrosion control functions. Its strong binding ability toward calcium, magnesium, and iron ions allows effective prevention of mineral deposition in cooling water systems, oilfield produced water, and membrane filtration applications.

EDTMPS is supplied as an amber transparent liquid, showing excellent resistance to hydrolysis and oxidation even under elevated temperatures. With balanced phosphonic acid groups and sodium salt stabilization, it performs consistently in cleaning agents, detergent formulations, and high-end water-treatment blends. For cooperation or customized specifications, please contact info@cntreechem.com.

Specification

Basic Information

Technical Specification

Applications

Water Treatment Industry – Circulating Cooling Water and Boilers

• Ethylenediamine tetra(methylene phosphonic acid) sodium salt (EDTMPS) is first and foremost a core scale inhibitor and corrosion-control agent in industrial water treatment, particularly in circulating cooling-water systems and boiler water. Its multi-phosphonic, nitrogen-containing structure gives strong multidentate chelation toward Ca²⁺, Mg²⁺, Ba²⁺, Sr²⁺ and other scaling ions, and it exhibits both classic chelation and pronounced lattice-distortion effects, so even low dosages can keep salts like calcium sulfate and calcium carbonate in solution or as loose, non-adherent particles instead of forming hard scale. In circulating cooling water, EDTMPS performs efficiently at elevated temperatures up to around 200 °C and is widely used in open and closed recirculating systems of power plants, chemical complexes and general industry, where it serves as a combined scale inhibitor and cathodic corrosion inhibitor for carbon steel.
• In cooling-water practice, EDTMPS is used either alone or, more commonly, in blends with other phosphonates and polymers. When applied on its own, typical use concentrations in the tower water are about 2–10 mg/L based on a 30 % active product, with concentrated solutions fed at 10–30 mg/L and dosed proportionally to make-up water; such single-component regimes are suited to simpler systems where dosing can be tightly controlled. In more demanding circuits, EDTMPS is combined with zinc salts to form synergistic packages in which 2–5 mg/L EDTMPS and 3–5 mg/L zinc sulfate together improve cathodic polarization and markedly increase corrosion inhibition on carbon steel compared with either component alone. For low-pressure boiler internal treatment, EDTMPS is frequently blended with HPMA (hydrolyzed polymaleic anhydride) in a 1:3 ratio and added at a total concentration of 5–15 mg/L to maintain clean tubes and high thermal efficiency under cyclic evaporation and concentration conditions.

Oilfield Water Injection and Reservoir Protection

• Water treatment in oilfields is the second major outlet for EDTMPS, especially in high-hardness, high-salinity injection-water systems and produced-water loops. Injection waters often contain substantial concentrations of Ca²⁺, Ba²⁺ and Sr²⁺, and mixing with formation water can rapidly drive sulfate and carbonate scales to supersaturation; EDTMPS retains its chelation capacity under these harsh conditions and prevents deposition of calcium sulfate, barium sulfate and similar scales on tubulars, downhole equipment and formation pore throats. Typical dosages in injection-water pipelines and wellheads range from 10–50 mg/L, with final dosing refined according to hardness level and scaling tendency. Its thermal and chemical stability at elevated temperatures and pressures means it continues to function effectively in deep wells where conventional inhibitors fail.
• To address particularly severe scaling and corrosive environments, EDTMPS is used in composite inhibitors with biodegradable polymers. A common high-hardness oilfield formulation combines EDTMPS and PASP (polyaspartic acid) in a 2:1 mass ratio at a total concentration of about 40 mg/L for systems with high mineralization, leveraging the strong chelation of EDTMPS and the dispersing and antifouling properties of PASP. For wells dominated by barium-sulfate scaling, specialized formulas use PASP:EDTMP ratios of 3:2 at around 50 mg/L dosage, providing targeted BaSO₄ control while maintaining integrity under reservoir conditions. Beyond injection water, EDTMPS is also incorporated into integrated long-term “clean and anti-scale” service programs, where its persistent multi-point binding to scale-forming ions allows extended runs between mechanical cleaning and ensures stable injection and production profiles.

Pulp and Paper Industry

• In the pulp and paper sector, EDTMPS functions primarily as a metal-ion control agent, scale inhibitor and water-quality stabilizer across pulping, stock preparation and papermaking circuits. Metal ions such as Fe³⁺, Mn²⁺ and Cu²⁺ can catalyze oxidative reactions leading to yellowing and embrittlement of paper, while hardness ions promote scale formation on washers, screens and heat exchangers. By chelating these ions, EDTMPS prevents adverse interactions with fibers and additives, thus reducing specks, color spots and loss of mechanical strength. During pulping, typical dosages of 5–15 mg/L are used to keep metal ions in soluble, non-reactive complexes, improving pulp brightness and stability.
• In the papermachine’s white-water and recirculation systems, EDTMPS is fed at 3–10 mg/L to stabilize water quality, maintaining consistent charge balance and reducing deposits that interfere with sheet formation and drainage. For more challenging circuits and evaporators, higher dosages around 10–20 mg/L are adopted in combination with dispersants and corrosion inhibitors to control scale on spray showers, strainers and evaporator heat-transfer surfaces. By keeping these systems clean, EDTMPS reduces unplanned shutdowns, extends felt and fabric life and supports steady-state operation with better strength and whiteness of the final paper.

Textile Printing and Dyeing Industry

• In textile printing and dyeing, EDTMPS is widely applied as a high-efficiency chelating agent and peroxide bleaching stabilizer. In dyeing processes, hard-water cations and trace metal ions promote the formation of insoluble dye-metal complexes that manifest as color spots, streaks and shade variations; EDTMPS at 0.5–2 g/L in dye baths complexes Ca²⁺, Mg²⁺ and transition metals, maintaining dyes in their intended solubilized or dispersed forms and ensuring level dyeing with bright, uniform shades. Its chelation across a wide pH range makes it compatible with many classes of dyes and auxiliaries.
• As an oxygen-bleach stabilizer, EDTMPS is used at 1–3 g/L alongside 3–10 g/L hydrogen peroxide in scouring and bleaching liquors at pH 9–11 and 90–100 °C, where it binds catalytic metal ions that otherwise decompose peroxide uncontrollably. This stabilizing effect yields gentler, more efficient bleaching with improved whiteness and less fiber damage, helping mills reduce rework and increase product quality. In pre-treatment auxiliaries for woven and knitted fabrics, EDTMPS is formulated at 0.5–1.5 % on fabric weight with wetting and refining agents to remove metal ions and deposits from fibers at an early stage, improving subsequent dye uptake and color-fastness while reducing equipment fouling by inorganic scale.

Daily Chemical and Personal-Care Industry

• In the daily chemical industry, EDTMPS is primarily used as a low-dosage chelating agent in detergents and personal-care formulations. In dishwashing liquids and household cleaners, a few tenths of a percent of EDTMPS (or EDTA-2Na replaced by EDTMPS) effectively binds metal ions in tap water, maintaining surfactant performance, preserving fragrance integrity and preventing color shift in the product during storage. In a typical dishwashing liquid formula containing linear alkylbenzene sulfonate, AES, fatty-acid alkanolamide, nonionic surfactants, preservative, caustic and salt, around 0.1 parts of EDTMPS serves as the chelating component, protecting sensitive ingredients and contributing to anti-scale and anti-spotting effects on dishes and glassware.
• In liquid laundry detergents, EDTMPS is used at about 0.1–0.5 % alongside 15–25 % surfactants and 10–20 % co-builders, primarily to sequester hardness ions, improve detergency and minimize incrustation on fabrics and machine parts. In cosmetics such as shampoos, body washes, lotions and creams, EDTMPS at 0.05–0.2 % acts as a formulation stabilizer: it complexes trace metals that would otherwise catalyze oxidation of oils, fragrances and colorants, thus extending shelf life and maintaining product appearance and sensory attributes. In shampoos and shower gels it helps maintain the activity of cleansing surfactants, while in emulsions and creams it protects lipid phases from rancidity and discoloration.

Pharmaceutical and Radiopharmaceutical Field

• In the pharmaceutical field, EDTMPS (or more strictly its acid form EDTMPA) plays a pivotal role as a chelating ligand in radiopharmaceuticals used for both diagnosis and therapy. Its multi-phosphonate structure provides high affinity for bone mineral and strong binding to radionuclide metal ions, enabling targeted delivery of radioactivity to bone tissue. Complexes such as ¹⁵³Sm-EDTMP are widely used for palliative treatment of bone metastasis pain: the ¹⁵³Sm-EDTMP complex preferentially accumulates in skeletal sites of high turnover, where emitted β-radiation alleviates pain and inhibits tumor growth while limiting exposure to soft tissues.
• EDTMP-based complexes are also prepared with ¹⁷⁷Lu and other therapeutic nuclides. Typical labeling conditions for ¹⁷⁷Lu-EDTMP involve around 25 mg of EDTMP, 100 µL of ¹⁷⁷LuCl₃ solution (12.8 MBq), pH adjusted to 8 and heating at 100 °C for about 30 minutes, producing stable complexes suitable for clinical application. Owing to its superior chelating performance, EDTMPA is considered a stronger chelator than EDTA or DTPA in many systems and can be substituted in a large share of applications where those classical agents were once used, with the added advantage of strong bone-seeking behavior when required.

Metal Processing and Electroplating Industry

• In metal processing, EDTMPS is used as both a multi-functional water-treatment component and a cyanide-free complexing agent in electroplating processes. In recirculating cooling water for rolling mills, pickling lines and other metal-processing equipment, its scale-inhibiting and corrosion-inhibiting properties protect heat exchangers, pipelines and spray systems, reducing maintenance and improving equipment life. As a surface-treatment component in metal-cleaning formulations, EDTMPS at 0.5–2 % works with surfactants, alkalis and solvents to dissolve oxide layers, complex metal ions and strip oils from steel, copper and aluminum, leaving clean, activated surfaces ready for coating, plating or further processing.
• In cyanide-free copper and imitation-gold plating systems, EDTMPS acts as one of the main complexing agents for metal ions. Typical cyanide-free copper baths use 50–200 g/L of EDTMPS or similar complexants with 1–10 g/L copper ions, plus brighteners and leveling agents, operating at pH 8–12 and moderate temperatures to deposit bright, compact copper coatings while avoiding cyanide emissions. In cyanide-free imitation-gold plating formulations, sulfate salts of copper and zinc, stannate, boric acid, citric acid and appropriate EDTMPS-based chelators are combined with potassium hydroxide to create alkaline baths that produce attractive gold-colored deposits without cyanide, phosphorus or ammonia, reducing environmental impact and worker exposure to hazardous substances.

Electronics and Semiconductor Industry

• The electronics industry uses high-purity EDTMPA and EDTMPS as critical chelating components in semiconductor wafer cleaning and precision electronics cleaning. Electronic-grade EDTMPA with purity around 99 % or higher and extremely low heavy-metal content is formulated into ultra-clean aqueous cleaning solutions that remove trace metallic contaminants from wafer surfaces during integrated-circuit manufacture. Its strong chelation helps lift and hold metal ions in solution while controlling etch rates so that underlying films and patterns are preserved, improving yield and device reliability.
• For printed-circuit boards and electronic assemblies, EDTMPS is incorporated as the chelating component in neutral, environmentally friendly, water-based cleaning agents. At 0.2–0.5 % levels together with carefully chosen surfactants and pH modifiers, it helps dissolve solder flux residues and metal contaminants without attacking copper traces, solder joints or component terminations. Advances in high-density interconnects and fine-line circuitry have made the cleanliness of boards and wafers more critical, and the high purity and low toxicity of EDTMPA/EDTMPS-based systems fit well with the move toward sustainable, halogen-free and low-residue cleaning chemistries.

Building Materials, Food and Other Emerging Applications

• In building materials, EDTMPS is used in concrete admixtures to improve durability and reduce cracking. By chelating calcium ions and moderating early hydration, it can be integrated into compound admixture systems to limit internal stress development and surface scaling, thereby enhancing durability and service life of concrete structures. In oil-well cementing, similar mechanisms help control setting behavior and maintain slurry stability in high-temperature, high-pressure environments, supporting secure zonal isolation and long-term integrity of wellbores.
• EDTMPS also has niche applications in the food industry and broader specialty-chemical markets. As a food-related additive, it can function as a chelating and anti-oxidation aid to prevent discoloration and oxidation of sensitive ingredients, extending shelf life within strict limits on dosage and purity. In advanced fields such as new-energy cooling fluids, high-end electronic cleaning and low-phosphorus green formulations, EDTMPS and its derivatives are being developed further as key components in low-toxicity, high-performance systems that respond to stricter environmental and performance requirements.

Storage & Handling

• Store in sealed plastic drums.
• Keep away from strong oxidizers and metal salts.
• Maintain dry, cool, and ventilated storage conditions.
• Use corrosion-resistant equipment during handling.
• Ground all equipment to prevent static accumulation.

Usage Notice

• Avoid contact with eyes and skin; wear suitable PPE.
• Do not mix with concentrated oxidizers.
• Test compatibility before blending with other chemicals.
• Follow local regulations for handling and transportation.
• A circulating cooling-water treatment program can use EDTMPS (30 % active) alone at 2–10 mg/L in the system water, corresponding to 10–30 mg/L of the concentrated product, to provide basic scale inhibition in relatively simple circuits.
• A synergistic cooling-water corrosion and scale inhibitor employs 2–5 mg/L EDTMPS with 3–5 mg/L zinc sulfate so that zinc accelerates cathodic polarization while EDTMPS supplies chelation and threshold inhibition for carbon steel systems.
• A low-pressure boiler internal treatment blend combines EDTMPS and HPMA in a 1:3 mass ratio at a total dosage of 5–15 mg/L to prevent carbonate and sulfate scales in drum boilers.
• In oilfield injection-water treatment, EDTMPS is dosed at 10–50 mg/L depending on water hardness and mineralization to control multi-component sulfate and carbonate scaling under high-temperature, high-pressure conditions.
• A high-hardness, high-mineralization oilfield water formulation uses EDTMPS and PASP in a 2:1 ratio at a total concentration of 40 mg/L so that the chelating and dispersing actions jointly inhibit scaling.
• A barium-sulfate-focused oilfield scale inhibitor package employs PASP and EDTMP in a 3:2 ratio at about 50 mg/L to control BaSO₄ deposition in wells prone to this specific scale.
• In pulp production, EDTMPS is added at 5–15 mg/L during pulping to control metal-ion levels, prevent discoloration and avoid metal-catalyzed degradation of fibers.
• In papermaking wet-end and white-water systems, EDTMPS is used at 3–10 mg/L to stabilize water quality, while 10–20 mg/L with dispersants and corrosion inhibitors protects circulation equipment from scaling and corrosion.
• A textile dyeing bath uses 0.5–2 g/L EDTMPS as a chelating agent to bind hardness ions and prevent color spots and shade differences caused by metal-dye complexes.
• A peroxide-bleaching liquor for textiles contains 1–3 g/L EDTMPS and 3–10 g/L hydrogen peroxide at pH 9–11 and 90–100 °C to stabilize the bleaching bath, prevent rapid H₂O₂ decomposition and protect fibers.
• A textile pre-treatment auxiliary applies EDTMPS at 0.5–1.5 % on fabric weight together with penetrants and refining agents to remove metal ions and impurities before dyeing.
• A dishwashing-liquid formulation includes about 0.1 parts EDTMPS (or EDTA-2Na) alongside LAS, AES, 6501, nonionic surfactants, preservative, caustic and salt to chelate metal ions, stabilize color and maintain fragrance.
• A liquid laundry detergent uses 0.1–0.5 % EDTMPS with 15–25 % surfactants and 10–20 % auxiliary builders so that hardness sequestration improves washing performance and reduces scale in washing machines.
• A cosmetics formulation such as shampoo or body wash incorporates 0.05–0.2 % EDTMPS as a chelating stabilizer to bind trace metals, maintain surfactant activity and prevent oxidation of oils and fragrances.
• A ¹⁵³Sm-EDTMP radiopharmaceutical for bone metastasis pain relief is prepared by reacting appropriate EDTMPA doses with ¹⁵³SmCl₃ at 37–111 MBq/kg under controlled pH 5–6 for about 30 minutes to form a stable bone-seeking complex.
• A ¹⁷⁷Lu-EDTMP therapeutic complex is prepared from 25 mg EDTMP and 100 µL ¹⁷⁷LuCl₃ solution (12.8 MBq) at pH 8 and 100 °C for 30 minutes to yield a radiopharmaceutical for targeted bone therapy.
• A cyanide-free copper electroplating bath uses 50–200 g/L EDTMPS or similar complexant, 1–10 g/L copper ions, trace brighteners and leveling agents at pH 8–12 and 20–40 °C to deposit bright, fine-grained copper coatings.
• A cyanide-free imitation-gold plating solution contains 20–25 g/L copper sulfate, 30–40 g/L zinc sulfate, 0–8 g/L sodium stannate, 20–30 g/L boric acid, 80–100 g/L citric acid, appropriate EDTMPS-based chelator and 80–110 g/L potassium hydroxide to produce decorative gold-colored deposits.
• A metal-cleaning agent for industrial parts formulates 0.5–2 % EDTMPS with 5–10 % surfactants, 10–20 % alkaline builders and suitable solvents to remove oils and oxides from steel and non-ferrous surfaces.
• A semiconductor-chip cleaning solution uses 0.1–1 % high-purity EDTMPA in deionized water to remove metallic contaminants from wafer surfaces and improve integrated-circuit yields.
• A neutral, environmentally friendly PCB cleaning agent includes 0.2–0.5 % EDTMPS as chelator together with 0.5–1 % surfactants and pH regulators to clean fine-pitch boards without damaging copper traces or components.
• An acidizing formulation for oilfield operations doses EDTMPS at 100–500 mg/L together with 15–20 % hydrochloric acid and suitable corrosion inhibitor to prevent scaling and corrosion during matrix acidization.
• A fracturing-fluid additive package adds 50–200 mg/L EDTMPS to the base fracturing fluid so that scale formation on proppant and equipment is restrained during high-pressure operations.

Packaging

• 25 kg plastic drum
• Customized packaging available upon request