2-아세틸부티로락톤 ABL 2-아세틸-γ-부티로락톤 CAS 517-23-7

트리켐 2-Acetylbutyrolactone (ABL) is a colorless transparent liquid with a mild odor, produced through controlled esterification and purification processes to ensure low water and impurity content. It features high solubility in most organic solvents and excellent performance as a reactive intermediate.

우리 manufacture and supply ABL across pharmaceutical synthesis, resin modification, fragrances, and polymer materials, ensuring consistent quality and reliable logistics. For product data or technical support, please reach us at info@cntreechem.com.

사양

기본 정보

기술 사양

응용 프로그램

제약 산업

• α-Acetyl-γ-butyrolactone (AABL, CAS 517-23-7) is a versatile five-membered lactone bearing an activated acetyl group, giving it strong reactivity in ring-opening, acylation, and condensation steps. It is widely adopted as a key intermediate for vitamin and CNS-drug syntheses where stable yields and controllable impurity profiles are essential. Its polarity and thermal stability also make it a dependable solvent or co-solvent in high-boiling reaction systems that require precise rate control.
• In vitamin routes, AABL participates in chlorination–hydrolysis–condensation sequences to generate core fragments for thiamine (Vitamin B1). In neuropsychiatric APIs, AABL feeds into lactam and ketone building blocks that are subsequently elaborated to agents such as risperidone/paliperidone; in anticonvulsant chemistry it serves as a masked carbonyl for constructing heterocycles under mild conditions. Process chemists value AABL for consistent reactivity, scalable workups, and compatibility with hydrogenation, halogenation, and amination stages.

농화학 산업

• AABL functions as a strategic synthon for modern fungicides and insecticide intermediates. Its acetylated lactone ring can be transformed into chlorinated acyl fragments or cyclopropyl derivatives that bridge directly into triazole-thione and azole frameworks. These fragments underpin broad-spectrum field products used on cereals, oilseeds, and specialty crops.
• Formulators also use AABL as a polar co-solvent in development batches for EC/SC systems when dissolving difficult actives or stabilizing premixes during high-shear milling. Its balance of solvency and boiling point helps minimize volatility losses while maintaining wetting and dispersion on leaf surfaces.

Battery and Energy Applications

• In aqueous Zn systems, AABL acts as a coordinating additive that complexes with Zn²⁺ and promotes a denser, more uniform deposition layer. This stabilizes cycling and suppresses dendrite growth in symmetric cells, extending runtime and improving coulombic efficiency at practical current densities.
• In Li-ion development work, AABL has been explored as a polar co-solvent or interfacial modifier within carbonate electrolytes and gel polymer matrices. Its carbonyl–lactone functionality aids controlled SEI formation, and its high boiling point supports low-temperature discharge and long-cycle tests in cathode-rich formulations.

코팅제, 잉크 및 접착제

• AABL serves as a reactive diluent/co-solvent that improves flow, leveling, and film integrity in epoxy, PU, acrylic, and polyester systems. By moderating evaporation rate and viscosity, it reduces pinholes and shrinkage while enhancing gloss and adhesion—attributes valued in automotive, protective, and industrial coatings.
• In printing inks, AABL’s solvency for resins and pigments supports clean transfer and stable viscosity windows in gravure and flexo lines. Specialty conductive/fluorescent inks also benefit from its high-boiling character, which balances open time with controlled drying to maintain line-edge definition.

Fragrance, Flavor, and Daily-Use Chemicals

• AABL is a productive starting point for lactone-type aroma chemicals delivering creamy, nutty, and fruity notes. Through amination/alkylation–cyclization sequences it yields thiazole and lactone favors used in bakery, seasoning, and tobacco flavor bases, where smoothness and warmth are desired.
• As a fixative/solvent in fragrance concentrates, AABL helps solubilize higher-MW components and improves radiance and longevity on substrates. Its mild odor profile and compatibility with common perfumery solvents make it easy to incorporate in household and personal-care fragrancing.

Polymers and Advanced Materials

• Via ring-opening polymerization, AABL produces poly(α-acetyl-γ-butyrolactone) and related copolymers with tunable modulus and degradation rates. These materials are explored for bio-absorbable uses and as flexible modifiers for polyesters and PU systems.
• AABL can be copolymerized or grafted to introduce adhesion, flexibility, or hydrolytic response in coatings and sealants. In processing, its solvency helps dissolve high-performance resins and enables clean film casting and impregnation steps.

Other Fine-Chemical Uses

• In dye and surfactant synthesis, AABL supplies acetylated C5 backbones that are elaborated to azo/anthraquinone intermediates or nitrogenous surfactants with favorable foaming–emulsifying balance. In lubricants, AABL-derived esters contribute to thermal stability and film strength for industrial and automotive fluids.
• As a laboratory workhorse, AABL’s carbonyl–lactone array offers a compact platform for building β-ketoesters, amino alcohols, and heterocycles under catalytic or base-mediated conditions, supporting diverse SAR and route-scouting programs.

보관 및 취급

• 에 저장 서늘하고 건조하며 통풍이 잘 되는 곳 locations.
• 접촉을 피하세요 strong oxidants, acids, or alkalis.
• 용기를 보관하세요 단단히 닫힘 to prevent hydrolysis or oxidation.
• 권장 보관 온도: 30°C 이하.
• 사용 stainless steel or HDPE drums 보관 및 운송을 위해.

사용 공지

• 아래쪽을 잡으세요 ventilation; avoid inhalation of vapor or direct skin contact.
• 사용 보호 장갑, 고글 및 보호복.
• Keep away from open flames and ignition sources.
• In case of leakage, absorb with inert material and dispose safely.
• 따르다 local chemical handling regulations for waste management.
• Vitamin B1 route intermediate: AABL (neat) through chlorination–hydrolysis–condensation — supplies core fragments for thiamine synthesis.
• Antipsychotic intermediate batch: AABL 1.0 eq, piperidine derivative 1.1 eq, base 1.5 eq, polar solvent q.s. — furnishes lactam/ketone blocks for CNS APIs.
• Fungicide precursor campaign: AABL → chlorinated acyl fragment via controlled halogenation — builds key unit for triazole-thione systems.
• Cyclopropylamine path: AABL to cyclopropyl intermediates under ring-transformation — delivers versatile insecticide building blocks.
• Zn battery electrolyte: 1.0 M ZnSO₄ + AABL 0.2–1.0 wt% + water balance — coordinates Zn²⁺ and stabilizes long-cycle plating/stripping.
• Li-ion gel electrolyte: carbonate solvents 85–95% + LiPF₆ 1.0 M + AABL 1–5% — promotes interfacial stability and low-temperature discharge.
• Epoxy coating grind: epoxy resin 60–70% + AABL 5–10% + solvent 15–25% + additives 2–5% — improves flow, adhesion, and anti-shrinkage.
• PU topcoat let-down: PU resin 55–65% + AABL 8–12% + co-solvent 10–20% + additives 2–5% — enhances leveling, gloss, and flexibility.
• Gravure ink base: pigment 15–25% + resin 20–35% + AABL 10–20% + solvents balance — stabilizes viscosity and printability.
• Flavor concentrate: aroma chemicals 80–90% + AABL 5–10% + fixatives 1–3% — boosts diffusion and retention in food/daily-use flavors.

포장

• 200kg 플라스틱 드럼
• 맞춤형 포장은 요청 시 가능합니다.