2-Pyrrolidinone α-PVR γ-Butyrolactam CAS 616-45-5

Tree Chem 2-Pyrrolidinone CAS 616-45-5 is a versatile solvent and intermediate with high polarity, low volatility, and superior chemical stability. It is used extensively in polymer production, lithium battery electrolyte systems, and pharmaceutical synthesis.

Our 2-Pyrrolidinone is available in Industrial and Electronic grades to meet diverse customer needs. Both grades are manufactured under strict purity control, ensuring minimal moisture and low γ-butyrolactone content. For inquiries or technical support, please contact info@cntreechem.com.

Спецификация

Основная информация

Технические характеристики

Приложения

Pharmaceutical Industry

• 2-Pyrrolidone serves as an essential intermediate in pharmaceutical synthesis, contributing to the production of cognitive enhancers, antibiotics, antivirals, cardiovascular, and neurological drugs. It is the key raw material for Piracetam, Nefiracetam, and Oxiracetam, which are widely used for improving brain function and treating neurological disorders. Due to its excellent solubility and chemical stability, 2-Pyrrolidone is also used as a solvent and reaction medium in drug manufacturing.
• In veterinary pharmaceuticals, it is often combined with PVP K15/K17 to create injectable formulations, serving both as a solvent and a chemical intermediate. Its versatility and low toxicity make it valuable in advanced pharmaceutical formulations requiring high-purity intermediates.

Agricultural Chemicals

• In the agrochemical sector, 2-Pyrrolidone functions as both a synthetic intermediate and a formulation solvent. It is used to synthesize novel herbicides like Dimepyrolimet and Tefurylchloramide, as well as fungicides and insecticides with strong bioactivity. In pesticide formulations, it acts as a co-solvent, stabilizer, or dispersing agent in emulsifiable concentrates (EC), suspension concentrates (SC), and water-dispersible granules (WG). These applications improve the solubility and bioavailability of active ingredients, making formulations more efficient and environmentally friendly.

Dyes and Pigments

• 2-Pyrrolidone is widely used in dye and pigment production, both as an intermediate and as a solvent. It participates in the synthesis of azo dyes, phthalocyanine dyes, and reactive dyes due to its strong polarity and high boiling point. In the dyeing process, it serves as a solvent and auxiliary agent in textile printing formulations, improving color dispersion, dye uptake, and stability. Its chemical inertness and compatibility make it a preferred solvent for high-performance pigment production and inkjet printing inks.

Electronics and Semiconductor Industry

• 2-Pyrrolidone plays a critical role in electronic chemical applications. It is the precursor for N-Methyl-2-Pyrrolidone (NMP), an essential solvent in lithium-ion battery manufacturing. Beyond that, 2-Pyrrolidone derivatives are found in semiconductor cleaning agents and printed circuit board (PCB) cleaning solutions, providing superior solvency and residue removal. Its derivatives are also used in the production of electronic-grade polymers and dielectric coatings, contributing to the miniaturization and reliability of advanced electronic components.

Other Applications

• In surfactants, 2-Pyrrolidone derivatives act as amphoteric agents with multiple hydrophilic groups, improving cleaning efficiency and surface wetting. In detergents, it serves as a co-solvent and solubilizer, enhancing the cleaning power of concentrated formulations. In coatings and inks, it functions as a coalescent and viscosity regulator, improving film formation and gloss. In polymer industries, it acts as a plasticizer and extraction solvent for aromatic compounds. In cosmetics, it serves as a penetration enhancer and solvent for active ingredients in skincare formulations.

Хранение и обработка

• Store in a cool, dry, well-ventilated place.
• Keep container tightly sealed to prevent moisture contamination.
• Избегайте контакта с oxidizing agents and strong acids.
• Использовать только stainless steel or glass containers.
• Handle under inert atmosphere for Electronic Grade materials.

Уведомление об использовании

• Avoid direct skin or eye contact; wear suitable protective gear.
• Ensure proper ventilation when handling in confined areas.
• Dispose of waste according to local environmental regulations.
• Piracetam synthesis: 2-Pyrrolidone reacts with methyl chloroacetate under mild heating to form pyrrolidone ethyl acetate, later aminolyzed to produce Piracetam.
• Nefiracetam synthesis: 2,6-Dimethylaniline, chloroacetyl chloride, and 2-Pyrrolidone condense in methanol to form a nootropic compound with 85% yield.
• Herbicide emulsifiable concentrate: Pesticide technicals with xylene solvent, 2-Pyrrolidone as co-solvent, and emulsifier enhance solubility and dispersion stability.
• Suspension concentrate: 2-Pyrrolidone derivative acts as dispersant and solubilizer with wetting and thickening agents to ensure uniform particle distribution.
• Dyeing assistant: A formulation of NMP 10–30%, dye 3–10%, urea 5–10%, and water uses 2-Pyrrolidone to improve color fastness and penetration.
• Electronic cleaning agent: A mixture containing N-Ethyl-2-Pyrrolidone and alcohol ethers removes photoresist residues while maintaining material integrity.
• Lithium battery electrolyte: Formulated with 5–11 parts of 2-Pyrrolidone, DMSO, and potassium methylsulfonylimide to improve conductivity and electrolyte stability.
• Coating additive: 2-Pyrrolidone serves as a coalescent and flow modifier in acrylic and styrene-acrylic systems, enhancing leveling and gloss.
• Detergent formulation: 2-Pyrrolidone solvent (4.2 parts) with glycols and surfactants increases solubility and overall detergent performance.
• Surfactant synthesis: N-Alkyl-propane-1,3-diamine and itaconic acid react with 2-Pyrrolidone to form amphoteric surfactants with excellent foaming and emulsifying ability.

Упаковка

• 200 kg plastic drum
• 200 kg iron drum
• Custom packaging available on request