2-Pyrrolidinone α-PVR γ-Butyrolactam CAS 616-45-5

Tree Chem manufactures and supplies high-purity 2-Pyrrolidinone (CAS 616-45-5), a colorless transparent liquid widely used in pharmaceuticals, electronics, and chemical synthesis. Available in Industrial and Electronic grades, the product offers excellent solubility and low impurity levels. For details or quotations, please contact info@cntreechem.com.

CAS: 616-45-5

Synonyms: γ-Butyrolactam; 1-Azacyclopentan-2-one; α-PVR

EINECS No.: 210-483-1

Molecular Formula: C₄H₇NO

Grade: Industrial / Electronic

Đóng gói: Thùng nhựa hoặc thùng sắt 200 kg

Chia sẻ:

Tree Chem 2-Pyrrolidinone CAS 616-45-5 is a versatile solvent and intermediate with high polarity, low volatility, and superior chemical stability. It is used extensively in polymer production, lithium battery electrolyte systems, and pharmaceutical synthesis.

Our 2-Pyrrolidinone is available in Industrial and Electronic grades to meet diverse customer needs. Both grades are manufactured under strict purity control, ensuring minimal moisture and low γ-butyrolactone content. For inquiries or technical support, please contact info@cntreechem.com.

Đặc điểm kỹ thuật

Thông tin cơ bản

Tham số	Giá trị
Tên sản phẩm	2-Pyrrolidinone
Số CAS.	616-45-5
Số EINECS.	210-483-1
Công thức phân tử	C₄H₇NO
Trọng lượng phân tử	85.10
Vẻ bề ngoài	Colorless clear liquid
Từ đồng nghĩa	γ-Butyrolactam; 1-Azacyclopentan-2-one; α-PVR;
Bao bì	Thùng nhựa 200 kg / Thùng sắt 200 kg

Thông số kỹ thuật

Mục	Đặc điểm kỹ thuật
Vẻ bề ngoài	chất lỏng trong suốt không màu
APHA Color (Pt-Co)	≤50
Xét nghiệm (%)	≥99.5 (GC)
γ-Butyrolactone (%)	≤0.1 (GC)
Polymer (%)	≤0.1 (GC)
Độ ẩm (%)	≤0,2

Ứng dụng

Ngành công nghiệp dược phẩm

2-Pyrrolidone serves as an essential intermediate in pharmaceutical synthesis, contributing to the production of cognitive enhancers, antibiotics, antivirals, cardiovascular, and neurological drugs. It is the key raw material for Piracetam, Nefiracetam, and Oxiracetam, which are widely used for improving brain function and treating neurological disorders. Due to its excellent solubility and chemical stability, 2-Pyrrolidone is also used as a solvent and reaction medium in drug manufacturing.
In veterinary pharmaceuticals, it is often combined with PVP K15/K17 to create injectable formulations, serving both as a solvent and a chemical intermediate. Its versatility and low toxicity make it valuable in advanced pharmaceutical formulations requiring high-purity intermediates.

Agricultural Chemicals

In the agrochemical sector, 2-Pyrrolidone functions as both a synthetic intermediate and a formulation solvent. It is used to synthesize novel herbicides like Dimepyrolimet and Tefurylchloramide, as well as fungicides and insecticides with strong bioactivity. In pesticide formulations, it acts as a co-solvent, stabilizer, or dispersing agent in emulsifiable concentrates (EC), suspension concentrates (SC), and water-dispersible granules (WG). These applications improve the solubility and bioavailability of active ingredients, making formulations more efficient and environmentally friendly.

Dyes and Pigments

2-Pyrrolidone is widely used in dye and pigment production, both as an intermediate and as a solvent. It participates in the synthesis of azo dyes, phthalocyanine dyes, and reactive dyes due to its strong polarity and high boiling point. In the dyeing process, it serves as a solvent and auxiliary agent in textile printing formulations, improving color dispersion, dye uptake, and stability. Its chemical inertness and compatibility make it a preferred solvent for high-performance pigment production and inkjet printing inks.

Ngành công nghiệp điện tử và bán dẫn

2-Pyrrolidone plays a critical role in electronic chemical applications. It is the precursor for N-Methyl-2-Pyrrolidone (NMP), an essential solvent in lithium-ion battery manufacturing. Beyond that, 2-Pyrrolidone derivatives are found in semiconductor cleaning agents and printed circuit board (PCB) cleaning solutions, providing superior solvency and residue removal. Its derivatives are also used in the production of electronic-grade polymers and dielectric coatings, contributing to the miniaturization and reliability of advanced electronic components.

Các ứng dụng khác

In surfactants, 2-Pyrrolidone derivatives act as amphoteric agents with multiple hydrophilic groups, improving cleaning efficiency and surface wetting. In detergents, it serves as a co-solvent and solubilizer, enhancing the cleaning power of concentrated formulations. In coatings and inks, it functions as a coalescent and viscosity regulator, improving film formation and gloss. In polymer industries, it acts as a plasticizer and extraction solvent for aromatic compounds. In cosmetics, it serves as a penetration enhancer and solvent for active ingredients in skincare formulations.

Lưu trữ & Xử lý

Bảo quản trong mát mẻ, khô ráo, thoáng khí place.
Giữ nguyên hộp đựng được niêm phong chặt chẽ Để ngăn ngừa sự nhiễm ẩm.
Tránh tiếp xúc với oxidizing agents and strong acids.
Chỉ sử dụng stainless steel or glass containers.
Handle under inert atmosphere for Electronic Grade materials.

Thông báo sử dụng

Avoid direct skin or eye contact; wear suitable protective gear.
Ensure proper ventilation when handling in confined areas.
Xử lý chất thải theo quy định môi trường địa phương.
Piracetam synthesis: 2-Pyrrolidone reacts with methyl chloroacetate under mild heating to form pyrrolidone ethyl acetate, later aminolyzed to produce Piracetam.
Nefiracetam synthesis: 2,6-Dimethylaniline, chloroacetyl chloride, and 2-Pyrrolidone condense in methanol to form a nootropic compound with 85% yield.
Herbicide emulsifiable concentrate: Pesticide technicals with xylene solvent, 2-Pyrrolidone as co-solvent, and emulsifier enhance solubility and dispersion stability.
Suspension concentrate: 2-Pyrrolidone derivative acts as dispersant and solubilizer with wetting and thickening agents to ensure uniform particle distribution.
Dyeing assistant: A formulation of NMP 10–30%, dye 3–10%, urea 5–10%, and water uses 2-Pyrrolidone to improve color fastness and penetration.
Electronic cleaning agent: A mixture containing N-Ethyl-2-Pyrrolidone and alcohol ethers removes photoresist residues while maintaining material integrity.
Lithium battery electrolyte: Formulated with 5–11 parts of 2-Pyrrolidone, DMSO, and potassium methylsulfonylimide to improve conductivity and electrolyte stability.
Coating additive: 2-Pyrrolidone serves as a coalescent and flow modifier in acrylic and styrene-acrylic systems, enhancing leveling and gloss.
Detergent formulation: 2-Pyrrolidone solvent (4.2 parts) with glycols and surfactants increases solubility and overall detergent performance.
Surfactant synthesis: N-Alkyl-propane-1,3-diamine and itaconic acid react with 2-Pyrrolidone to form amphoteric surfactants with excellent foaming and emulsifying ability.